Name the bacterial helicase loader that helps load the helicase at the origin.

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Multiple Choice

Name the bacterial helicase loader that helps load the helicase at the origin.

Explanation:
Bacterial replication begins when the initiator protein binds the origin to open the DNA, and a dedicated loader then delivers and assembles the helicase at the unwound region. The helicase loader binds the helicase DnaB and guides its loading onto the single-stranded DNA at the origin, forming a complex that positions and activates the helicase. Once DnaB is properly loaded, the loader dissociates and primase can be recruited to start primer synthesis. This loader’s role is distinct from the other proteins: DnaA is the initiator that starts the origin opening, DnaB is the helicase that unwinds DNA, and DnaG is the primase that makes RNA primers. Therefore, the helicase loader is DnaC.

Bacterial replication begins when the initiator protein binds the origin to open the DNA, and a dedicated loader then delivers and assembles the helicase at the unwound region. The helicase loader binds the helicase DnaB and guides its loading onto the single-stranded DNA at the origin, forming a complex that positions and activates the helicase. Once DnaB is properly loaded, the loader dissociates and primase can be recruited to start primer synthesis. This loader’s role is distinct from the other proteins: DnaA is the initiator that starts the origin opening, DnaB is the helicase that unwinds DNA, and DnaG is the primase that makes RNA primers. Therefore, the helicase loader is DnaC.

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